Validation of String Test for Diagnosis of Helicobacter pylori Infections

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Validation of string test for diagnosis of Helicobacter pylori infections.

The method of recovering Helicobacter pylori DNA or viable cells absorbed on a string that a person has swallowed and that is retrieved an hour later (string test) should be a useful alternative to traditional analysis of cells or DNA obtained by endoscopy, which is invasive, uncomfortable, relatively costly, and ill-suited for community-based and pediatric studies. Here we assayed the sensitiv...

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[Validation of a simplified 13C-urea breath test method for the diagnosis of Helicobacter pylori infection].

OBJECTIVE To validate a simplified 13C-urea breath test (13C-UBT) method for the diagnosis of H. pylori infection. MATERIAL AND METHODS Patients referred for gastrointestinal endoscopy and biopsy were included, and a 13C-UBT was performed after a 6-hour fast. Breath samples were collected in 10 ml glass tubes before and 30 min after the simultaneous administration of 50 mg of 13C-urea and 2 g...

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Validation of a rapid stool antigen test for diagnosis of Helicobacter pylori infection.

The aim of this study was to validate the rapid lateral flow Helicobacter pylori stool antigen test (One step H. pylori antigen test, ACON laboratories, San Diego, USA; Prime diagnostics, São Paulo), using 13C-Urea Breath Test as the gold standard for H. pylori infection diagnosis. A total of 98 consecutive patients, asymptomatic or dyspeptic, entered the study. Sixty-nine were women, with a me...

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Diagnosis of Helicobacter pylori.

Several techniques have been proposed to diagnose H. pylori infection based either on the direct or indirect detection of the bacteria. [table: see text] The current direct methods are performed on biopsy specimens obtained at endoscopy. Histological examination must always be performed because in addition to H. pylori detection it allows observation of the lesions present. Culture, while more ...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 2006

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.44.3.976-980.2006